Hardware benchmark
Scoring 42 Million Protein Variants a Day on AWS Trainium2
João Correia, Telmo Felgueira, Tiago Gonçalves, Bojan Jakimovski, Jim Burtoft, Louise Ping · August 18, 2026
A native PyTorch benchmark showing EvolutionaryScale ESMC-300M running on AWS Trainium2: 490.8 variants per second on a single trn2.3xlarge — approximately 42.4 million protein variants scored per day at approximately $1.26 per million, 60% below H100 in this fixed-shape D2Deep benchmark.